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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC18
All Species:
20
Human Site:
S388
Identified Species:
40
UniProt:
Q5T9S5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T9S5
NP_996769.2
1454
168962
S388
C
Q
Q
E
I
E
S
S
R
V
E
L
R
S
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537071
1456
169626
S390
C
Q
Q
E
I
E
S
S
R
V
E
L
R
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q640L5
1455
169723
S391
C
Q
Q
D
I
D
N
S
R
V
E
L
K
S
L
Rat
Rattus norvegicus
XP_001060717
1462
170487
S390
C
Q
Q
D
I
D
N
S
R
V
E
L
R
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508531
925
106760
R9
E
F
C
S
L
K
C
R
E
K
D
D
E
E
E
Chicken
Gallus gallus
XP_001232490
1295
151316
S358
K
E
K
N
V
L
V
S
E
N
A
E
L
R
A
Frog
Xenopus laevis
Q9PW73
1335
154049
A381
D
Q
P
K
E
Q
P
A
D
S
A
S
D
G
S
Zebra Danio
Brachydanio rerio
XP_692712
779
89837
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
K747
A
K
S
D
D
D
K
K
K
C
A
E
A
I
M
Sea Urchin
Strong. purpuratus
XP_796315
2152
245292
S397
C
Q
G
D
I
E
N
S
R
E
Q
L
Q
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LW85
726
81954
Baker's Yeast
Sacchar. cerevisiae
P25386
1790
206434
Y610
K
S
L
L
S
F
S
Y
Q
I
Q
D
E
D
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
90.1
N.A.
84.4
83.5
N.A.
41.4
49.3
39.8
22.7
N.A.
N.A.
N.A.
20.2
22.9
Protein Similarity:
100
N.A.
N.A.
95.4
N.A.
92.4
91.4
N.A.
51
65.2
59.5
37.2
N.A.
N.A.
N.A.
40
40
P-Site Identity:
100
N.A.
N.A.
100
N.A.
73.3
80
N.A.
0
6.6
6.6
0
N.A.
N.A.
N.A.
0
53.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
20
26.6
26.6
0
N.A.
N.A.
N.A.
33.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.7
40.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
9
0
0
25
0
9
0
9
% A
% Cys:
42
0
9
0
0
0
9
0
0
9
0
0
0
0
0
% C
% Asp:
9
0
0
34
9
25
0
0
9
0
9
17
9
9
0
% D
% Glu:
9
9
0
17
9
25
0
0
17
9
34
17
17
9
9
% E
% Phe:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
42
0
0
0
0
9
0
0
0
9
0
% I
% Lys:
17
9
9
9
0
9
9
9
9
9
0
0
9
9
0
% K
% Leu:
0
0
9
9
9
9
0
0
0
0
0
42
9
0
42
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
9
0
0
25
0
0
9
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% P
% Gln:
0
50
34
0
0
9
0
0
9
0
17
0
9
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
42
0
0
0
25
9
0
% R
% Ser:
0
9
9
9
9
0
25
50
0
9
0
9
0
34
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
9
0
9
0
0
34
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _